Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRush University Medical Center

About this trial

The purpose of this study is to determine differences in pain, functional patient reported outcomes, and objective imaging parameters following non-operative and meniscus root repair treatment. Furthermore, the long-term goal of this research proposal is to understand the natural history of meniscal root tears and their subsequent repair, in order to better determine risk factors for inferior outcomes and progression to osteoarthritis (OA).

Eligibility criteria

Qualifiers

MRI-verified isolated tibial medial meniscus root tear

Subject must be 18 years of age or older

Disqualifiers

Concurrent ligamentous knee pathology requiring surgical intervention (i.e. anterior cruciate ligament tear, posterior cruciate ligament tear, posterolateral corner injury, high-grade medial collateral ligament tear),

Preoperative Kellgren-Lawrence grade of 3 or 4

Inability to complete outcome questionnaires or comply with required postoperative imaging or MRI requirements, or medical contraindications to surgery or physical therapy.

There will be no exclusion criteria regarding body mass index (BMI) or mechanical alignment, however subjects will be stratified in groups for further analysis (BMI less and over 35 and varus alignment below and over 3º of varus).

Trial design

Treatments tested in this trial

  • Non-Operative Pain Management
  • Operative treatment arm will undergo transtibial medial meniscus root repair within 3 weeks of enrollment

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Rush University Medical Center

Lead sponsor

International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine

Collaborator