Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorSpitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"

About this trial

Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.

Eligibility criteria

Qualifiers

Patients admitted into one of the specified wards of the involved hospitals

Patients aged 18-60 years

Suspected meningitis, encephalitis, stroke or cerebral tumors

Disqualifiers

Age under 18 years or over 60 years old

Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma)

Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)

Trial design

Treatments tested in this trial

  • Optic Nerve Sheath Diameter

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators