About this trial
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.
Eligibility criteria
Qualifiers
Patients admitted into one of the specified wards of the involved hospitals
Patients aged 18-60 years
Suspected meningitis, encephalitis, stroke or cerebral tumors
Disqualifiers
Age under 18 years or over 60 years old
Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma)
Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)
Trial design
Treatments tested in this trial
- Optic Nerve Sheath Diameter
Treatment groups
Sponsors and collaborators
Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"
Lead sponsor
Institutul Clinic Fundeni
Collaborator