Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
Sponsorjiaoliqun

About this trial

To evaluate the clinical significance of optical coherence tomography (OCT) in interventional treatment of intracranial atherosclerotic stenosis (ICAS).

Eligibility criteria

Qualifiers

Symptomatic ICAS. Participants with ICAS with a transient ischaemic attack (TIA) or stroke attributable to the territory of the stenotic artery were defined as symptomatic. A TIA was defined as a transient episode of neurological dysfunction (focal weakness or language disturbance, transient monocular blindness, or required assistance in walking) caused by focal brain or retinal ischaemia that lasted for at least 10 minutes but resolved within 24 hours

Stenotic degree ≥ 50%, measured by digital subtraction angiography

The stenosis must located in at least one major intracranial artery (internal carotid artery, vertebral artery, middle cerebral artery, or basilar artery)

Disqualifiers

Arteriovenous Malformation

Aneurysm

Trial design

Treatments tested in this trial

  • Optical Coherence Tomography
  • Percutaneous transluminal angioplasty and stenting

Treatment groups

400 Participants
are divided into 2 treatment groups

Sponsors and collaborators

jiaoliqun

Lead sponsor

Xuanwu Hospital, Beijing

Sponsor institution