Optimization of Patient Preparation and Imaging Techniques for Cardiac CT

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKarolinska University Hospital

About this trial

The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels (CCTA). Globally, approximately one-third of patients experience heart-related conditions. Because the heart is a moving organ, imaging presents challenges. A higher heart rate requires increased scanning power, which results in more images and, in some cases, higher radiation exposure that may be harmful. To address this issue, beta-blocker medication is administered before the examination to lower the heart rate. This medication can be given orally, intravenously, or both. While this approach is effective, the most optimal method remains uncertain.

The objectives of this study are:

* To determine whether oral administration of beta-blockers is as effective as intravenous administration in maintaining a stable heart rate during CT imaging. * To assess whether listening to music during the procedure improves patient comfort and overall experience.

Participants will:

* Be randomly assigned to one of four groups: * One group will receive beta-blocker medication orally. * Another group will receive beta-blocker medication intravenously. * One group will listen to music during the procedure. Participants will report their sensations and experiences before, during, and after the examination.

The study investigators will compare the effectiveness of oral and intravenous beta-blockers, as well as the impact of music, in terms of:

* Heart rate stability and reduction. * Participant-reported comfort and overall experience.

Eligibility criteria

Qualifiers

Participant with a preexisting referral for a Cardiac CT examination

Age 18 years or older

Disqualifiers

Age under 18 years

Atrial fibrillation

Pacemaker

Participation in clinical drug trials

Trial design

Treatments tested in this trial

  • Metoprolol I.V.
  • Metoprolol I.V. and 1 hour waiting.
  • Music Intervention, Seloken (Recordati) orally and Metoprolol I.V.

Treatment groups

240 Participants
are divided into 4 treatment groups

Sponsors and collaborators