Optimizing Aerobic Fitness in Older Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorUniversity of Vermont Medical Center

About this trial

Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.

Eligibility criteria

Qualifiers

>65 years old

ambulatory

enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited

Disqualifiers

have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)

unwilling to comply with the exercise prescription they may be assigned to

have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio <1.0

Trial design

Treatments tested in this trial

  • HIIT
  • MICT

Treatment groups

114 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Vermont Medical Center

Lead sponsor

National Institute on Aging (NIA)

Collaborator