Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing
ConditionHypothyroidism
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorUniversity of Michigan
About this trial
The proposed study focuses on testing a novel adapted evidence-based multilevel intervention, Deprescribing Thyroid Hormone In Older Adults (D-THIO), to support thyroid hormone deprescribing (dose de-escalation and/or discontinuation) in older adults with thyroid hormone overtreatment and/or misuse and reduce patient harm. Findings from this study will lay the groundwork for broad implementation of D-THIO and serve as a model for deprescribing inappropriate medications for other endocrine conditions and conditions with biochemical monitoring.
Eligibility criteria
Qualifiers
age 65 years and older
on thyroid hormone therapy and have a serum Thyroid-stimulating hormone (TSH) <0.5 mIU/L or are on thyroid hormone therapy for an inappropriate indication
English speaking
without cognitive impairment
Disqualifiers
None
Trial design
Treatments tested in this trial
- D-THIO (Deprescribing Thyroid Hormone In Older Adults)
- Enhanced usual care
Treatment groups
900 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Michigan
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov