Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorShanghai Zhongshan Hospital
About this trial
This study aims to evaluate the impact of high-risk factors-such as elevated portal venous pressure, concurrent large extra-luminal vessels, portal vein thrombosis, and prominent portosystemic shunts-on the efficacy of endoscopic therapy. By comparing with interventional treatment, the goal is to optimize the clinical management protocol for esophageal and gastric varices, enhance the therapeutic outcomes of portal hypertension-related esophageal and gastric varices, and improve patient prognosis.
Eligibility criteria
Qualifiers
Admitted due to gastrointestinal bleeding and clinically diagnosed with portal hypertension
Underwent imaging examinations and gastroscopy within one week after admission
Gastroscopy revealed the presence of esophageal and/or gastric varices
Age over 18 years
Disqualifiers
Previous history of liver transplantation
Imaging or gastroscopy findings indicated ulcers or other causes of gastrointestinal bleeding
Concurrent severe life-threatening diseases involving the circulatory, hematological, or respiratory systems
Difficulty in follow-up, or lack of essential medical history information, imaging data, or other necessary records
Trial design
Treatments tested in this trial
- Not listed
Trial groups
1,066 Participants
are grouped into 2 trial groupsLocations
Sponsors and collaborators
Shanghai Zhongshan Hospital
Lead sponsor
RenJi Hospital
Collaborator
Shandong Provincial Hospital
Collaborator
Qilu Hospital of Shandong University
Collaborator
Third Affiliated Hospital, Sun Yat-Sen University
Collaborator
Nanfang Hospital, Southern Medical University
Collaborator
The First Affiliated Hospital of Nanchang University
Collaborator
Shanghai East Hospital
Collaborator
Shanghai Changzheng Hospital
Collaborator
Second Military Medical University
Collaborator
The General Hospital of Northern Theater Command
Collaborator
Source ClinicalTrials.gov