Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Colorado, Denver
About this trial
The objective is to determine the effectiveness of pulsatile flow during cardiopulmonary bypass to reduce the incidence of acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during cardiopulmonary bypass.
Eligibility criteria
Qualifiers
Able to provide informed consent
Scheduled for elective cardiac surgery with cardiopulmonary bypass
Disqualifiers
Emergency procedures
Scheduled for heart or lung transplantation
Scheduled for ventricular assist device implantation
Use of the Medtronic Elongated Once-Piece Arterial Cannula
Trial design
Treatments tested in this trial
- Non-pulsatile blood flow
- Pulsatile blood flow
Treatment groups
1,100 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Colorado, Denver
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov