About this trial
The goal of this prospective, cohort study is to learn about smell, taste and trigeminal dysfunction in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). The research team hypothesizes that treatment with allo-HSCT will induce:
* Distortion of taste and smell and trigeminal functions like cooling, tingling, and burning sensations. * Reduced saliva production leading to oral dryness and dental caries. * Changes in the connectivity of the taste-, smell- and pain-cortical brain regions.
Eligibility criteria
Qualifiers
None
Disqualifiers
disorders affecting the oral cavity including poor tooth-status
those using drugs affecting the gustatory/olfactory functions
those with brain disorders
those who have a chronic disorder affecting the immune system, have cancer or who are pregnant.
Trial design
Treatments tested in this trial
- Not listed