Oral, Chemosensory and Trigeminal Functions in Allo-HSCT

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age30-70
SponsorUniversity of Oslo

About this trial

The goal of this prospective, cohort study is to learn about smell, taste and trigeminal dysfunction in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT). The research team hypothesizes that treatment with allo-HSCT will induce:

* Distortion of taste and smell and trigeminal functions like cooling, tingling, and burning sensations. * Reduced saliva production leading to oral dryness and dental caries. * Changes in the connectivity of the taste-, smell- and pain-cortical brain regions.

Eligibility criteria

Qualifiers

None

Disqualifiers

disorders affecting the oral cavity including poor tooth-status

those using drugs affecting the gustatory/olfactory functions

those with brain disorders

those who have a chronic disorder affecting the immune system, have cancer or who are pregnant.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

70 Participants
are grouped into 2 trial groups

Sponsors and collaborators