Oral Immunotherapy for Egg Allergy in Children Aged 6 to 16
ConditionEgg Allergy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-16
SponsorTampere University Hospital
About this trial
The aim of the study is to determine the efficacy of a 12-month egg oral immunotherapy (OIT) protocol with a cooked whole egg product including yolk and egg white.
Study hypothesis: With this method the risk for severe allergic reaction to egg protein is reduced and the diet can partly or completely be normalized.
Eligibility criteria
Qualifiers
Age 6 to 16 years
Elevated spesific serum IgE to egg (> 5 kU/l) and/or positive skin prick to egg allergen
Positive oral food challenge for egg or anaphylaxis reaction to egg within the 6 months
Diet free from egg in any form
Disqualifiers
Age less than 6 years or more than 16 years
Poor asthma control or uncontrolled asthma
Severe/significant cardiovascular disease
Autoimmune disease
Trial design
Treatments tested in this trial
- Egg product including egg white and yolk allergens
Treatment groups
60 Participants
are divided into 4 treatment groupsSponsors and collaborators
Tampere University Hospital
Lead sponsor
University of Oulu
Collaborator
Oulu University Hospital
Collaborator
Source ClinicalTrials.gov