Oral Immunotherapy With Egg in Infants
ConditionFood Allergy in Infants
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-36
SponsorJosefine Gradman
About this trial
In children allergic to egg, oral immunotherapy (OIT) with egg may accelerate that the children grow out of the food allergy.
Children than have a positive oral food provocation with egg with a low threshold, will be offered to start OIT. This means that the child have to ingest a small amount of egg every day.
Once a year, the child will undergo a new oral food provocation to investigate if the child is still allergic to egg or not.
The age of the children at time of this acquired tolerance will be compared with a historical cohort of children with egg allergy.
Eligibility criteria
Qualifiers
positive specific IgE to egg
positive oral provocation for egg
low threshold
Disqualifiers
uncontrolled astham treatment with biologics or immunsupressive drugs treatment with antihistamines
Trial design
Treatments tested in this trial
- low-dose OIT egg
Treatment groups
40 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Josefine Gradman
Lead sponsor
Odense University Hospital
Sponsor institution
Source ClinicalTrials.gov