Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorTanta University
About this trial
This study aims to compare the efficacy of using Melatonin versus Pregabalin on postoperative pain and anxiety after spine surgeries.
Eligibility criteria
Qualifiers
Patients aged 21-60 years old.
Both sexes.
Patients of American Society of Anesthesiologists (ASA) physical status I & II.
Undergoing elective spine surgery.
Disqualifiers
Patient refusal.
History of allergic reactions to melatonin or pregabalin.
Patients with cardiovascular disease (ischemic heart disease, Heart Failure, Arrythmia, Heart Block).
Patients with kidney disease with (plasma creatinine level > 1.5mg/dl).
Trial design
Treatments tested in this trial
- Placebo capsule
- Melatonin capsule
- Pregabalin capsule
Treatment groups
105 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov