Orexin Gene in Anorexia Nervosa
ConditionAnorexia Nervosa
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorIstituto Auxologico Italiano
The objectives of this study will be to determine the methylation of the promoter of the Orexin A (OX-A) and B (OX-B) genes in young women (\> 18 years) with Anorexia Nervosa (AN), compared with a control group; and to evaluate the relationship of promoter methylation of the genes for OX-A and OX-B with the severity of the eating disorder, psychiatric comorbidities (in particular, depression), and sleep quality.
Female sex
Age 18 years and older
Anorexia Nervosa
Hospitalized at the Division of Eating and Nutrition Disorders, Istituto Auxologico Italiano, IRCCS, Piancavallo, Italy
Absence of signed informed consent
Female sex
Age 18 years and older
Body Mass Index between 18.5 and 24.9 kg/m2