About this trial
To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.
Eligibility criteria
Qualifiers
Adult (age ≥ 18 to 95 years) patients with an occlusion of the internal carotid artery or M1 or M2 segment of the middle cerebral artery,;
Patients with a score of at least 6 on the National Institutes of Health Stroke Scale (NIHSS) at admission and a score of 0 or 1 on the modified Rankin scale before the onset of stroke;
Patients with a score of at least 6 on the Alberta Stroke Program Early CT score (ASPECTS) value;
Baseline multimodal-CT imaging, including NCCT, CTA and CTP, performed at the trial-site hospital
Disqualifiers
Stoke of large artery atherosclerotic origin or other determined factors (such as dissection) or tandem occlusion;
Patients underwent rescue angioplasty or stenting after thrombectomy
Trial design
Treatments tested in this trial
- rapid local ischemic postconditioning (RL-IPostC)
Treatment groups
Sponsors and collaborators
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead sponsor
Zhangzhou Municipal Hospital of Fujian Province
Collaborator