Oriental Research AlliaNce of Acute Ischemic Stroke Given Endovascular Treatment

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-95
SponsorShanghai Jiao Tong University Affiliated Sixth People's Hospital

About this trial

To determine the safety and efficacy of in situ ischemic postconditioning immediately after successful reperfusion in AIS patients underwnet EVT.

Eligibility criteria

Qualifiers

Adult (age ≥ 18 to 95 years) patients with an occlusion of the internal carotid artery or M1 or M2 segment of the middle cerebral artery,;

Patients with a score of at least 6 on the National Institutes of Health Stroke Scale (NIHSS) at admission and a score of 0 or 1 on the modified Rankin scale before the onset of stroke;

Patients with a score of at least 6 on the Alberta Stroke Program Early CT score (ASPECTS) value;

Baseline multimodal-CT imaging, including NCCT, CTA and CTP, performed at the trial-site hospital

Disqualifiers

Stoke of large artery atherosclerotic origin or other determined factors (such as dissection) or tandem occlusion;

Patients underwent rescue angioplasty or stenting after thrombectomy

Trial design

Treatments tested in this trial

  • rapid local ischemic postconditioning (RL-IPostC)

Treatment groups

160 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Lead sponsor

Zhangzhou Municipal Hospital of Fujian Province

Collaborator