Orthostatic And Postprandial Hypotension In Hospitalized Older Adults (HOPE65)

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorUniversity Medical Centre Ljubljana

About this trial

The goal of this observational study is to determine how often orthostatic hypotension and postprandial hypotension occur in adults aged 65 years and older who are hospitalized in internal medicine departments.

Orthostatic hypotension is defined as an excessive drop in blood pressure after standing up from a lying or sitting position. Postprandial hypotension is an excessive drop in blood pressure that occurs after eating a meal. These conditions can increase the risk of falls, fainting, loss of independence, and other health problems in older adults.

The main questions this study aims to answer are:

* How common orthostatic hypotension and postprandial hypotension are in hospitalized adults aged 65 years and older. * Whether these conditions are associated with medication use, chronic diseases, and geriatric syndromes (such as frailty, cognitive impairment, and functional decline).

Participants will:

* have blood pressure measured while lying down and standing * have blood pressure measured after a meal * undergo a comprehensive geriatric assessment, including evaluation of functional status, cognitive function, frailty, mobility, and nutritional status * provide information about medications and medical history * be followed for up to 12 months to record outcomes such as falls, syncope, hospitalization, and death

Eligibility criteria

Qualifiers

Age 65 years or older

Hospitalization in internal medicine departments at the University Medical Centre Ljubljana

Duration of hospitalization ≥48 hours

Hemodynamic stability confirmed by the treating physician

Disqualifiers

Medical condition preventing study procedures (e.g., need for continuous supine position)

Inability to provide informed consent

Refusal to participate

Severe cognitive impairment or delirium

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

500 Participants
are grouped into 1 trial group