OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVA Office of Research and Development

About this trial

Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone. This is especially true in residential settings where both disorders are more severe than outpatient settings. Obstructive sleep apnea (OSA) is highly comorbid with both disorders and untreated OSA is associated with worse functional impairment across multiple domains, worse quality of life, worse PTSD, higher suicidal ideation, and higher substance use and relapse rates. Treating OSA with evidence-based positive airway pressure (PAP) in Veterans with SUD/PTSD on a residential unit is a logical way to maximize treatment adherence and treatment outcomes. This study compares OSA treatment while on a SUD/PTSD residential unit to a waitlist control group. The investigators hypothesize that treating OSA on the residential unit, compared to the waitlist control, will have better functional, SUD, and PTSD outcomes.

Eligibility criteria

Qualifiers

a Veteran of the U.S. military or Reserve/National Guard member

at least 18 years of age

have an AHI 5 per hour

experienced trauma that occurred in childhood or adulthood; at least one month post-trauma

Disqualifiers

have central sleep apnea (AHI >=5 and > 50% central apneas)

arrives on the SARRTP unit already using a PAP device (Veteran's previously diagnosed with OSA, but not using PAP therapy will be eligible)

the SARRTP medical staff advises against the study based on medical history and physical examination; d) history of severe cognitive impairment (via MOCA < 26)

history of psychosis or mania independent of substance use will be excluded because the presence of these disorders can impede therapy progress

Trial design

Treatments tested in this trial

  • Positive Airway Pressure Device

Treatment groups

194 Participants
are divided into 2 treatment groups