Outcome of 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism
ConditionPrimary Aldosteronism
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorQifu Li
About this trial
To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)
Eligibility criteria
Qualifiers
None
Disqualifiers
Combined with autonomous cortisol secretion, cortisol after 1mg dexamethasone suppression test (DST) ≥50 nmol/l.
PA patients who meet the by-passing AVS criteria [i.e., younger than 35 years old, spontaneous hypokalemia, adrenal CT indicated unilateral low-density adenoma (≥1cm), plasma aldosterone >300pg/ml]
Suspicion of familial hyperaldosteronism or Liddle syndrome. [i.e., age <20 years, hypertension and hypokalemia, or with family history]
Suspicion of pheochromocytoma or adrenal carcinoma.
Trial design
Treatments tested in this trial
- 68Ga-Pentixafor PET/CT
Treatment groups
320 Participants
are divided into 2 treatment groupsSponsors and collaborators
Qifu Li
Lead sponsor
Chongqing Medical University
Sponsor institution
The Affiliated Hospital Of Southwest Medical University
Collaborator
West China Hospital
Collaborator
Tongji Hospital
Collaborator
The First Affiliated Hospital of Zhengzhou University
Collaborator
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Collaborator
The Third Xiangya Hospital of Central South University
Collaborator
Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborator
Changzhi Medical College
Collaborator
Xiangya Hospital of Central South University
Collaborator
Source ClinicalTrials.gov