Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
ConditionSoft Tissue Sarcoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAmsterdam UMC
About this trial
The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the extremities. A secondary objective is to assess the influence of different variables (e.g., radiotherapy, ethnicity, etc.) on body image, health-related QoL, and functioning.
Patients who underwent a surgical resection at the Amsterdam UMC between 2010 and 2021 will be approached to participate in the study. Participants will complete four questionnaires and undergo a physical examination. Additionally, they will have a 3D gait analysis, a 6-minute walk test with gas analysis, and a muscle strength assessment. Furthermore, muscle volume change will be evaluated on pre- versus postoperative MRI scans.
Eligibility criteria
Qualifiers
Treated with surgical resection for primary non-metastatic extremity STS at the Amsterdam UMC between 2010-2021.
Being able to visit the Amsterdam UMC, location AMC once or twice.
Pregnant patients must agree to be scheduled 5 months after their pregnancy ends.
Disqualifiers
Patients who cannot maintain 6 minutes of walking will be excluded from the 6-minute walk test.
Trial design
Treatments tested in this trial
- Surgical resection with or without radiotherapy and/or chemotherapy
Treatment groups
150 Participants
are divided into 1 treatment groupSponsors and collaborators
Amsterdam UMC
Lead sponsor
Amsterdam UMC, location AMC
Sponsor institution
Source ClinicalTrials.gov