About this trial
The study is a quasi-experimental investigation of a sub-acute stabilization center (SASC) for people who have had or are at risk for having an opioid overdose and have an encounter with Seattle Fire Department emergency medical services (EMS) in Seattle, WA. Those transported to the SASC are the intervention participants and two comparison groups will be utilized: eligible Seattle EMS patients who opt not to go to the SASC and King County residents, outside of Seattle, who meet the same eligibility criteria. A comparative interrupted time series analysis is planned to study the main effectiveness outcomes.
Seattle Fire EMS will assess, refer, and arrange transport for participants to the SASC. The SASC will offer an array of services including post-overdose monitoring, utilization of buprenorphine and methadone for the treatment opioid use disorder and opioid withdrawal, linkage to ongoing care for OUD, and provision of harm reduction services and supplies. The length of stay in the SASC will be limited to less than 24 hours. A continuous process improvement (CPI) approach will monitor and refine the intervention. Characterization of the interventions will be based upon analysis of service utilization patterns over time along with interviews and surveys with stakeholders.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Verbally consents to transfer of care to SASC.
Awake and oriented to person and place, with no significant deficits in mental status or neurological function.
Age >=18
Patent airway and effective respirations with adequate oxygenation.
Disqualifiers
None
Trial design
Single group
Treatments tested in this trial
Sub-acute stabilization
BehavioralThe sub-acute stabilization center (SASC) is for people who have had or are at risk for having an opioid overdose and have an encounter with Seattle Fire Department emergency medical services (EMS) in Seattle, WA. Those transported to the SASC are the intervention participants and two comparison groups will be utilized: eligible Seattle EMS patients who opt not to go to the SASC and King County residents, outside of Seattle, who meet the same eligibility criteria. A comparative interrupted time series analysis is planned to study the main effectiveness outcomes. Seattle Fire EMS will assess, refer, and arrange transport participants to the SASC. The SASC will offer an array of services including post-overdose monitoring, utilization of buprenorphine and methadone for the treatment opioid use disorder and opioid withdrawal, linkage to ongoing care for OUD, and provision of harm reduction services and supplies. The length of stay in the SASC will be limited to less than 24 hours.
Treatment groups
Trial outcomes
Primary outcomes
Repeat opioid overdose
One of more opioid overdoses after enrollment
MOUD initiation
Starting opioid use disorder treatment with buprenorphine, methadone or naltrexone
MOUD retention
Having one or more additional doses prescribed, administered or dispensed of buprenorphine, methadone, or naltrexone
Emergency department utilization
Having one or more all-cause emergency department admission
Other outcomes
Service utilization patterns
Changes in the way services or opioid-related emergencies are provided and changes to cascade of care changes over time (descriptive).
Staff observations
How care opioid-related care is viewed by SASC staff members (descriptive).
Continuous process improvement (CPI) partner observations
How care opioid-related care is viewed by CPI partners and participants (descriptive).
Sponsors and contacts
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University of Washington
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator