About this trial
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are:
1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COPCs compared with youth with localized pain conditions and healthy controls. 2. If disrupted nociceptive processing at baseline is associated with the transition from a single localized pain condition to COPCs in youth.
Participation includes:
* quantitative sensory testing * blood draw * sleep assessment * questionnaires
Eligibility criteria
Qualifiers
General Criteria
Access to the internet either by laptop, tablet, or phone (for REDCap Surveys)
English-speaking
Parent or guardian willing to comply with protocol, complete study assessments, and provide written informed consent
Disqualifiers
General Criteria
Skin conditions (e.g., eczema) or past skin damage on the arms and legs in or near sites of sensory testing
Any comorbid rheumatic disease (e.g., arthritis, lupus), neurological (e.g., epilepsy, traumatic brain injury) or medical condition (e.g., cancer, diabetes)
Control Specific Criteria
Trial design
Treatments tested in this trial
- Conditioned Pain Modulation
- Offset Analgesia
- Spatial Summation
- Temporal Summation