Oxalate-Driven Host Responses in Kidney Stone Disease
ConditionKidney Stones
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Alabama at Birmingham
About this trial
This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS). Participants will be in this study for about 3 weeks, consume controlled diets, and provide blood and urine specimens.
Eligibility criteria
Qualifiers
Men and women between the ages of 18 and 60 years old.
Able to provide informed consent.
BMI between 20-30 kg/m2.
Non-tobacco users or not pregnant/breastfeeding/nursing.
Disqualifiers
Failure to meet the inclusion criteria or physician refusal.
Inability to sign and read the informed consent.
Any medical, psychiatric, or social conditions that would prohibit participants from abiding by the study requirements.
BMI ˃30 kg/m2 and <20 kg/m2
Trial design
Treatments tested in this trial
- Low Oxalate Diet
- High Oxalate Diet
Treatment groups
88 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Alabama at Birmingham
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Source ClinicalTrials.gov