Pain & Reward Neuromodulation of CNS Circuits
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorDuke University
About this trial
This pilot feasibility study aims to evaluate transcranial magnetic stimulation (TMS) targeting the prefrontal cortex in patients with fibromyalgia syndrome (FMS). The study will assess preliminary efficacy and mechanisms of central nervous system changes using neuroimaging, behavioral tasks, sensory testing, and neuroimmune markers. Participants will undergo MRI scans, multi-day TMS sessions, and complete questionnaires. The goal is to generate pilot data for future trials on neuromodulation for chronic pain.
Eligibility criteria
Qualifiers
Female and ages 18 +
Ability to read/understand English and give consent to participate
Physician diagnosis & confirmation of primary fibromyalgia syndrome
Verbal agreement to maintain dose of prescribed medication (if any) constant throughout the study, except exclusion medication and except if there is a medical emergency requiring changes in medication
Disqualifiers
None
Trial design
Treatments tested in this trial
- Transcranial Magnetic Stimulation (TMS)
Treatment groups
30 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Duke University
Lead sponsor
American Fibromyalgia Syndrome Association
Collaborator
Source ClinicalTrials.gov