PARAtracheal vs CRIcoid Pressure on GLIttic DEformation (PARAGLIDE)
ConditionAirway Management
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Liege
About this trial
This randomized crossover study evaluates the effects of left paratracheal pressure, cricoid pressure, and no pressure on glottic visualization during videolaryngoscopy in adult surgical patients. The primary endpoint is the Percentage of Glottic Opening (POGO) score assessed by blinded video review. Secondary endpoints include anatomical measures (glottic surface area, vertical and horizontal displacement of the glottic plane) and clinical outcomes (first-pass success, first-pass success without desaturation \<90%, intubation time, Intubation Difficulty Scale, hypoxemia, hemodynamic events, airway trauma, and postoperative sore throat or dysphonia). All outcomes are collected from routine anesthetic practice and video analysis, with no additional procedures.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Scheduled for elective surgery under general anesthesia requiring endotracheal intubation
ASA physical status I or II
Normal airway anatomy as assessed by the anesthesiologist (Mallampati I-II, no known or anticipated difficult airway)
Disqualifiers
History of difficult intubation or anticipated difficult airway
Known upper airway anatomical abnormalities (e.g., tumors, tracheal deviation, cervical spine instability)
BMI > 35 kg/m²
Gastroesophageal reflux disease or increased aspiration risk
Trial design
Treatments tested in this trial
- Cricoid Pressure (30 N)
- Left Paratracheal Pressure (30 N)
Treatment groups
50 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov