Pathogen-microbiome Interaction During Helicobacter Pylori Infection
ConditionHelicobacter Pylori Infection
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Freiburg
About this trial
Helicobacter pylori affects the gut microbiome in ways that are only partially understood. In which patients H. pylori causes severe disease and in whom it merely colonizes, possibly even with beneficial effects, is not understood. The investigators are pursuing the hypothesis that changes in the gut microbiome that can be easily measured in stool have such predictive value.
Eligibility criteria
Qualifiers
Male and female patients aged ≥ 18 years.
Specimens from patients undergoing tissue sampling, stool, and blood to rule out Helicobacter pylori infection
Written informed consent from patients.
Male and female (non-pregnant) volunteers between the ages of 18-65 years.
Disqualifiers
Minor patients
Patients not capable of giving consent
Samples without sufficient residual material after standard diagnostic procedures
Samples from patients who have not given consent for testing
Trial design
Treatments tested in this trial
- Analysis of gut microbiome and immune signatures
Treatment groups
180 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov