Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorQianfoshan Hospital

About this trial

This study aims to reveal the immune and inflammatory regulatory molecular mechanisms related to the progression of allergic bronchopulmonary aspergillosis (ABPA), and to build a precision typing based on inflammation and identify the biomarkers of typing, and to explore the clinical outcomes of different inflammatory phenotypes.

Eligibility criteria

Qualifiers

Meets the diagnostic criteria for allergic bronchopulmonary aspergillosis.

Meets the diagnostic criteria for fungal-sensitized asthma.

Disqualifiers

Human immunodeficiency virus infection.

Malignant tumor.

Blood system disease.

autoimmune system disease.

Trial design

Treatments tested in this trial

Treatment groups

140 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Qianfoshan Hospital

Lead sponsor

Shanghai Pulmonary Hospital, Shanghai, China

Collaborator

Fudan University

Collaborator

Guizhou Provincial People's Hospital

Collaborator

The First Hospital of Jilin University

Collaborator

Qilu Hospital of Shandong University

Collaborator