Pathophysiological Study of the Sensitive Scalp

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorUniversity Hospital, Brest

About this trial

Sensitive skin is defined as a syndrome manifested by the occurrence of unpleasant sensations (tingling, burning, pain, pins and needles) in response to stimuli that should not normally cause them. These unpleasant sensations cannot be explained by lesions attributable to a specific skin disease. Sensitive skin can affect different parts of the body. The scalp is a site that is often affected, with specificity linked in particular to the presence of hair and different triggering factors (styling habits, wearing of head coverings, application of cosmetics to the scalp, etc.). Sensitive scalp affects around half the population, and can have an impact on the quality of life of sufferers, particularly those whose symptoms are very intense. Women are more likely than men to have a sensitive scalp, so in order to have a more homogenous study population, we chose to include 40 women. The pathophysiology of sensitive skin is imperfectly understood, and studies specific to the sensitive scalp are very rare. However, the pathophysiology of the sensitive scalp could be different because it is a hairy area, more innervated, and less exposed to environmental factors.

Eligibility criteria

Qualifiers

Adult women without dermatosis

Collection of free and informed consent

patient affiliated to a social security scheme

Disqualifiers

Refusal to take part in the study

Dermatosis of the scalp (psoriasis, seborrhoeic dermatitis, etc.)

Pregnant and breast-feeding women

Women under legal protection (guardianship, curatorship)

Trial design

Treatments tested in this trial

  • A scalp biopsy using a 4 mm punch in the retroauricular hair zone
  • a general health questionnaire
  • Questionnaires concerning their sensitive scalp
  • Collection of skin microbiota

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators