About this trial
As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve tasks people have trouble doing in everyday life. Transcranial electrical stimulation uses small amounts of electricity to try to alter brain functioning. These approaches may help improve cognitive abilities like attention, learning, memory, finding words, and problem solving as well as everyday functioning. The goal of this study is to identify how to best use these methods, either alone or in combination.
Eligibility criteria
Qualifiers
Individuals who have reported cognitive dysfunction and cognitively intact participants.
Participants will be age 50 or older
Disqualifiers
A history of epilepsy
Sensory or motor impairments that limit the ability to take part in the study
Current alcohol or drug abuse/dependence
Those who are currently pregnant or may become pregnant during the duration of the study (if there is a question of pregnancy, pregnancy tests will be available for participants at no charge)
Trial design
Treatments tested in this trial
- Active tDCS
- Sham tDCS
- Cognitively based intervention
- Active tACS
- Sham tACS
- Active tRNS
- Sham tRNS
Treatment groups
7
Treatment groupsSee each treatment group below.