Patient-derived Organoids of Lung Cancer to Test Drug Response

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Geneva

About this trial

This is a single center, single arm, open and exploratory clinical study, with 50 cases planned for a period of 3 years. The purpose of this study is to evaluate the consistency and accuracy of a Patient-Derived Organoid (PDO) Model of lung cancer to predict the clinical efficacy of anti-cancer drugs, in order to predict the best chemotherapy regimen for each given patient.

Eligibility criteria

Qualifiers

Histologically proven lung cancer

Age ≥ 18

Written informed and signed consent

Accessible to biopsy and/or surgery sample of metastasis and/or primitive tumour

Disqualifiers

Less than 18 years of age

Not able to give informed consent (language, intellectual capacities, etc.)

Not accessible to biopsy and/or surgery sample

Not enough lung tissue for a histological analysis or the remaining lung tissue is not enough to perform a routine pathological analysis.

Trial design

Treatments tested in this trial

  • Lung tumor resection

Treatment groups

No treatment groups listed

Sponsors and collaborators