Patient-derived Tumor-like Cell Clusters Predict Progesterone Sensitivity in Patients With Early Endometrial Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age17-45
SponsorPeking University People's Hospital

About this trial

To construct a prediction model of progesterone sensitivity in patients with endometrial cancer treated with fertility preservation

Eligibility criteria

Qualifiers

Have a confirmed pathological diagnosis based upon hysteroscopy: atypical endometrial hyperplasia or histologically prove well-differentiated EEC G1 without myometrial invasion

No signs of suspicious extrauterine involvement on enhanced magnetic resonance imaging (MRI) or enhanced computed tomography (CT) or ultrasound

Have a desire for remaining reproductive function or uterus

Good compliance with adjunctive treatment and follow-up

Disqualifiers

Acute liver disease or liver tumor (benign or malignant) or renal dysfunction

Pregnancy or potential pregnancy

Confirmed diagnosis of any cancer in reproductive system

Acute severe disease such as stroke or heart infarction or a history of thrombosis disease

Trial design

Treatments tested in this trial

  • No intervention

Treatment groups

244 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Peking University People's Hospital

Lead sponsor

Peking University

Collaborator

Beihang University

Collaborator