Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity Hospital, Ghent

About this trial

Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications. However, they still face challenges such as difficult catheter navigation and incomplete embolization.

This study aims to improve the efficiency and safety of endovascular procedures by developing new preoperative planning methodologies. These methodologies involve mapping the cerebral vasculature and creating computational fluid dynamics (CFD) and artificial intelligence (AI) models to simulate blood flow. By using these models, interventional radiologists can better plan catheter navigation and predict embolization outcomes. This could lead to faster, more accurate procedures with reduced radiation exposure for patients.

Eligibility criteria

Qualifiers

Subjects who are diagnosed with aneurysm or arteriovenous malformation

Subjects who are treated (or will be treated) with endovascular embolization and/or arteriovenous coiling

During and before/after the subject's intervention, medical images (MRI, 3D rotational angiography, DSA) were collected of the cerebral arterial vascular tree (which can be used to develop patient-specific models), including catheter location and use of contrast fluid to visualize the cerebral to make the arterial tree more visible.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Endovascular treatment

Treatment groups

500 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University Hospital, Ghent

Lead sponsor

University Ghent

Collaborator