Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention

ConditionSquamous Cell Carcinoma of Oropharynx

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorRegina Elena Cancer Institute

About this trial

Prospective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune response

Eligibility criteria

Qualifiers

Squamous cell carcinomas of the oropharynx (OPSCC) candidates for surgical

Age > 18 years

ECOG performance status <_ 2

Signature of informed consent (to participate in the study and data processing)

Disqualifiers

Presence of distant metastases at the time of diagnosis

Previous head and neck cancer

Trial design

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

Regina Elena Cancer Institute

Lead sponsor

University of Campania Luigi Vanvitelli

Collaborator

Federico II University

Collaborator

I.R.C.C.S. Fondazione Santa Lucia, Italy

Collaborator

Source ClinicalTrials.gov