Pediatric Arm of DZL All Age Asthma Cohort

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-18
SponsorLMU Klinikum

About this trial

Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).

Eligibility criteria

Qualifiers

informed consent by parents (and by children if age > 8 years)

age 6 months to 18 years

term delivery (≥ 37 weeks)

active/passive understanding of German

Disqualifiers

known inborn or perinatal pulmonary disease

airway malformation

oxygen therapy after birth with a duration of more than 24 hours

ventilator support or mechanical ventilation after birth

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

1,500 Participants
are grouped into 3 trial groups

Sponsors and collaborators

LMU Klinikum

Lead sponsor

German Federal Ministry of Education and Research

Collaborator

German Center for Lung Research

Collaborator

Comprehensive Pulmonary Center Munich

Collaborator

Airway Research Center North

Collaborator

Biomedical Research in Endstage and Obstructive Lung Disease Hannover

Collaborator

Translational Lung Research Center Heidelberg

Collaborator

Universities of Giessen and Marburg Lung Center

Collaborator