About this trial
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).
Eligibility criteria
Qualifiers
informed consent by parents (and by children if age > 8 years)
age 6 months to 18 years
term delivery (≥ 37 weeks)
active/passive understanding of German
Disqualifiers
known inborn or perinatal pulmonary disease
airway malformation
oxygen therapy after birth with a duration of more than 24 hours
ventilator support or mechanical ventilation after birth
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
LMU Klinikum
Lead sponsor
German Federal Ministry of Education and Research
Collaborator
German Center for Lung Research
Collaborator
Comprehensive Pulmonary Center Munich
Collaborator
Airway Research Center North
Collaborator
Biomedical Research in Endstage and Obstructive Lung Disease Hannover
Collaborator
Translational Lung Research Center Heidelberg
Collaborator
Universities of Giessen and Marburg Lung Center
Collaborator