About this trial
The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic inflammation, while the intake of less heated products might cause disease recidive. Moreover, we would like to study whether the gradual re-introduction of less heated products after the most heated form is tolerated, could lead to tolerance induction in EoE.
Eligibility criteria
Qualifiers
None
Disqualifiers
Children younger than 12 months
Children with active pedEoE
Children who refuse to adhere to the protocol
Children with associated IgE mediated hen's egg and/or cow's milk allergy with specific IgE antibody titers that predict active (baked egg and/or baked milk) food allergy with cut-off titers as used at the consultation of allergy (KLL). Those children will become eligible however if their titers decrease while the study is still open.
Trial design
Treatments tested in this trial
- Implementation of cow's milk in decreasingly heated forms
- Implementation of hen's egg in decreasingly heated forms