PEPPI Study: Identification of Women at Risk for Placental Dysfunction

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorOulu University Hospital

About this trial

The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a Finnish general population.

Condition or disease: pre-eclampsia, intrauterine growth restriction, polycystic ovary syndrome

Eligibility criteria

Qualifiers

Pregnant (first trimester)

Understands Finnish

≥18 years

Signed informed consent

Disqualifiers

Multiple pregnancy

Miscarriage/termination of the index pregnancy

No first trimester blood sampling

Participates in PEPPI-study (criteria above)

Trial design

Treatments tested in this trial

  • Pre-eclampsia screening program

Treatment groups

3,000 Participants
are divided into 6 treatment groups

6

Treatment groups

See each treatment group below.

Sponsors and collaborators

Oulu University Hospital

Lead sponsor

PerkinElmer, Inc.

Collaborator

Roche Diagnostics GmbH

Collaborator

Academy of Finland

Collaborator

Sigrid Jusélius Foundation

Collaborator

Finnish Medical Foundation

Collaborator

University of Oulu

Collaborator