The investigation aims to demonstrate initial safety and efficacy of the AngioVac System for the removal of vegetation in the right heart in patients with infective endocarditis.
Subject age ≥ 18 years
Subject provides a signed and dated Informed Consent Form
Subject has a diagnosis of native infective endocarditis
Subject has presence of bacteremia with valvular (tricuspid or pulmonic) vegetations > 1 cm confirmed by transesophageal echocardiogram (TEE) or transthoracic echocardiogram (TTE) with the presence of septic emboli
Subject requires debulking of vegetation on cardiac leads
Subject has a prior history of ischemic/hemorrhagic stroke (within 3 months)
Subject has a coagulation disorder
Subject has arterial septic emboli