Performance of Large Language Models for Structured Recognition and Refractive Prediction

ConditionCataract
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorJin Yang

About this trial

We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error metrics; secondary outcomes included decision-support performance for toric IOL selection and agreement on ordered T-codes. No clinical intervention was performed.

Eligibility criteria

Qualifiers

None

Disqualifiers

incomplete biometric data on the examination report;

a history of previous ocular surgery or ocular trauma

the occurrence of intraoperative complications, such as an anterior capsular tear or posterior capsular rupture

the development of significant postoperative complications, including but not limited to severe intraocular infection or inadequate pupillary dilation.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

Jin Yang

Lead sponsor

Eye & ENT Hospital of Fudan University

Sponsor institution