Performances on Cognitive Functions and Brain Function and Follow-up After Different Treatments in Patients With Autonomous Cortisol Secretion: a Single-center, Prospective, Observational Study

ConditionsAutonomous Cortisol Secretion Adrenal Incidentaloma Non-functioning Adrenal Adenomas

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age20-65

SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

About this trial

This is a single center, prospective, observational study to explore and evaluate the differences on cognitive function and brain function by functional-MRI in autonomous cortisol secretion patients, and the different treatments methods on the cognitive function and brain function in patients with autonomous cortisol secretion

Eligibility criteria

Qualifiers

age 20-65 years;

≥ 6 years of education；

right-handed;

complete entire cognitive function tests;

Disqualifiers

< 6 years of education;

age < 20 years or > 65 years;

maximum diameter of AI <1cm;

active malignancies;

Trial design

Treatments tested in this trial

Cognitive function assessment; functional magnetic resonance imaging
laparoscopic adrenal surgery

Treatment groups

62 Participants

are divided into 2 treatment groups

Sponsors and collaborators

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Lead sponsor

Source ClinicalTrials.gov