About this trial
The goal of this observational study is to learn whether high abdominal pressure or low blood flow pressure to the kidneys is linked to kidney injury after heart surgery. The main questions it aims to answer are:
Does high abdominal pressure increase the risk of kidney injury after cardiac surgery?
Can low blood flow pressure to the kidneys help predict who may develop kidney problems?
Participants in this study are adults undergoing heart surgery, such as coronary artery bypass grafting (CABG) or valve surgery. Researchers will measure abdominal pressure and blood pressure continuously before and after surgery using medical devices that are already part of routine care. This study does not involve any changes to standard treatment.
Participants will:
Have their abdominal and blood pressures continuously monitored using existing devices
Have blood and urine tests to check kidney function
Be followed during their hospital stay and up to 30 days after surgery to assess outcomes like length of stay, readmission, and survival
This study takes place at two hospitals-one in Poland and one in the United States. Researchers hope the findings will help identify early warning signs of kidney injury and improve monitoring practices after heart surgery.
Eligibility criteria
Qualifiers
Age 18 years or older
Undergoing cardiac surgery (CABG, valve surgery, combined procedures, heart transplantation, or placement of assist device)
Expected hospital stay of at least one night
Preoperative serum creatinine measurement available
Disqualifiers
Age below 18 years
Incarcerated individuals
No requirement for urinary catheter placement
Presence of a do-not-resuscitate (DNR) order
Trial design
Treatments tested in this trial
- Continous IAP measurement
Treatment groups
Locations
Sponsors and collaborators
Medical University of Lublin
Lead sponsor
Wake Forest University Health Sciences
Collaborator