Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire Vaudois

About this trial

The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery. The main question to be answered is whether the PENG block is equivalent to intrathecal morphine in reducing postoperative pain.

Participants will be randomised into two groups. Patients assigned to the PENG group will receive spinal anaesthesia with local anaesthetic (isobaric bupivacaine) alone and a PENG block. Patients assigned to the intrathecal morphine (ITM) group will receive spinal anaesthesia with a mixture of local anaesthetic (isobaric bupivacaine) and morphine (100 mcg) and a sham PENG block to ensure patient blinding.

Eligibility criteria

Qualifiers

Male and female patients

ASA (American Society of Anaesthesiologists) I-III

18 years of age or older

Patients scheduled for elective primary hip arthroplasty

Disqualifiers

Refusal or inability to give consent

Allergy to any of: ropivacaine, paracetamol, ibuprofen, ketorolac, morphine, ondansetron or dexamethasone

Bleeding diathesis

Neurological deficit of the operative side

Trial design

Treatments tested in this trial

  • Intrathecal morphine
  • Pericapsular nerve group block (PENG)

Treatment groups

80 Participants
are divided into 2 treatment groups