Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTanta University
About this trial
This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role against chronic phantom pain in patients undergoing lower limb amputation surgery
Eligibility criteria
Qualifiers
Patients of both genders, suffering from vascular insufficiency of one or both lower limbs and scheduled for above or below knee amputation under general anesthesia.
Disqualifiers
Patients with a history of allergy to local anesthetics.
Patients with allergy to methylene blue.
Anticoagulant use or coagulopathy.
Trial design
Treatments tested in this trial
- Bupivacaine methylene blue
- bupivacaine saline
Treatment groups
72 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov