About this trial
The goal of this clinical trial is to determine whether sodium bicarbonate fluoride toothpaste can help maintain periodontal health in adults who have undergone non-surgical periodontal treatment. The main question it aims to answer is:
Does daily use of toothpaste affect the following outcomes: clinical oral health (plaque scores, gingival bleeding scores and periodontal pocket depths), salivary biochemical markers and the oral microbiome.
Outcomes measures will be recorded at 0,3, and 6 months, during which time participants will receive either the treatment or placebo toothpaste and undergo oral hygiene instruction and PMPR over 6 months.
Eligibility criteria
Qualifiers
Adult participants >18 years, of any gender will be recruited.
Disqualifiers
Full dentures
Diabetics
Cancer diagnosis
Pregnancy
Trial design
Treatments tested in this trial
- no treatment received
- Periodontal treatment and OHI
- Periodontal treatment and OHI
Treatment groups
Sponsors and collaborators
University of Plymouth
Lead sponsor
HALEON
Collaborator