Periodontal Microbiota of Patients Candidates for Bariatric Surgery With Body Mass Index Greater Than 30

ConditionsBariatric Surgery Obesity, Morbid

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversity Hospital, Toulouse

About this trial

The goal of this observational study is to compare the microbiological composition of the periodontal plaque of obese people undergoing bariatric surgery according to their Body Mass Index. The main question it aims to answer is:

Does obese patients have different microbiote according to their obesity?

Obesity being classified in two groups :

* group "obesity" for a BMI between 30 and 35 * versus "morbid obesity" group with a BMIabove 35.

Participants who are scheduled to undergo bariatric surgery as part of their regular medical care will answer questions about their quality of life, hygiene habits, and saliva and periodontal samples will be taken.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

BMI greater than or equal to 30

Be on the list of patients scheduled for bariatric surgery,

Be able to receive information about the study and understand the information form in order to take part in the study. This implies mastering the French language,

Disqualifiers

Alcohol consumption >30g/d (men) or 20g/d (women),

Having taken antibiotics, prebiotics or probiotics in the month prior to inclusion (this has an influence on the composition of the patient's microbiota),

During pregnancy or breastfeeding,

For whom oral surgery is planned (surgery for benign or malignant tumours of the maxillary and mandibular bone bases), or with a history of oral surgery in the month prior to inclusion,

Trial population

Obese patients scheduled to undergo bariatric surgery

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

170 Participants

are grouped into 2 trial groups

Group A: Group 1 : obesity : 30 ≤ BMI < 35

Group B: Group 2 : morbid obesity : 35 ≤ BMI

Trial outcomes

Primary outcomes

Taxonomic analysis

Taxonomic analysis of the microbiological composition of the periodontal plaque between group 1 (obesity) and 2 (morbid obesity) : relative quantities of periodontal bacteria between group 1 (obesity) and 2 (morbid obesity)

Time frame

before bariatric surgery

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital, Toulouse

Lead sponsor

Source ClinicalTrials.gov

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