Postoperative delirium is common in patients undergoing cardiovascular surgery and associated with poor outcomes. However the pathogenesis of postoperative delirium is poorly understood. Multichannel electroencephalogram is a recognized tool for identifying neurophysiologic states during anesthesia, sleep, and arousal. The aim of the current study is to evaluate the mechanisms and predictors of postoperative delirium in patients undergoing cardiovascular surgery using electroencephalogram.
age of at least 18 years
normal cognitive function at the time of enrollment evidenced by a Mini-Mental State Examination (MMSE) score of more than 24 of 30
Chinese Mandarin as the native language
providing informed consent
pre-existing delirium assessed according to the Confusion Assessment Method (CAM)
history of neurological or psychiatric disease
impaired vision or auditory function which may effect the assessments
unwillingness to participate in the study