About this trial
Intraventricular conduction delay alone or in combination with AV conduction delay is associated with a dyssynchronous activation of the ventricles and may result in LV function impairment.
Conduction system pacing can restore physiologic ventricular activation in the presence of intraventricular and atrioventricular conduction delays.
Patients with intraventricular conduction delay alone or in combination with AV conduction delay who have a permanent pacemaker indication due to intermittent bradycardia and have predominantly intact AV conduction may benefit from continuous CSP.
Eligibility criteria
Qualifiers
age > 18 years
Any indication for cardiac pacing with an expected VP burden ≤ 10% after 1- month run-in period
Baseline wide QRS (≥150 ms) with normal PR or QRS ≥ 130 ms + PR≥230 ms
LVEF≥50%
Disqualifiers
Pregnant woman
Permanent or long-lasting atrial fibrillation
Previous PM/ICD
Unstable angina, acute Myocardial Infarction (MI), Coronary Artery Bypass Graft (CABG), Percutaneous Coronary Angioplasty (PCI), surgical valve repair or replacement within 90 days prior enrollment
Trial design
Treatments tested in this trial
- Pacemaker implant
Treatment groups
Sponsors and collaborators
Óscar Cano Pérez
Lead sponsor
Spanish Society of Cardiology
Sponsor institution