Personalized Digital Training Intervention to Reduce Inflammation by Correcting Pathological Movement Patterns in Pre-stage Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorCharite University, Berlin, Germany

About this trial

Osteoarthritis (OA) is a condition that causes pain and stiffness in the joints, often due to injuries like torn ligaments. Even after surgery, these injuries can lead to long-term joint problems. Current treatments don\'t fully prevent OA from developing. This study is testing a new 12-week exercise program designed to improve how the knee moves, using a special sensor-based system. The goal is to reduce joint inflammation and prevent the development of OA in patients who have had knee surgery.

Eligibility criteria

Qualifiers

Signed written informed consent

Adult subjects between 18 to 50 years old at the time of screening

Primary ACL reconstruction within a maximum of 6 months after a unilateral ACL injury

Complete baseline assessment between 8 and 12 weeks after ACL reconstruction

Disqualifiers

Significant trauma to a weight-bearing joint within 12 months prior to study initiation (excluding the ACL injury)

Previous surgeries on the study knee (except for the ACL reconstruction)

Signs of knee OA as defined by the OARSI-Joint Space Narrowing (JSN) Score of two or more (standing AP x-ray)

Physical activity level: Tegner activity score before injury of 0-2 (very low activity) or 8-10 (very high activity)

Trial design

Treatments tested in this trial

  • Training intervention

Treatment groups

60 Participants
are divided into 2 treatment groups