Personalized Innovative Intervention Pathways to Promote EF in Children With CP

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age5-13
SponsorIRCCS Fondazione Stella Maris

About this trial

Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range of impairments, including cognitive impairments. In general, multiple clinical characteristics that define and determine different functional profiles. Several studies on children with unilateral and bilateral CP have been shown that, despite the overall preserved intellectual functioning, there are specific neuropsychological impairments distinguishing the two forms, including deficits in different Executive Functions (EF) components. Executive Functions (EFs) represent a complex cognitive domain consisting of a set of top-down functions essential for adaptive goal-directed behaviour, allowing to formulate, plan, and organise ideas, cope with challenges and novelties, resist temptations and stay focused. EF represents general domain abilities transversal to several cognitive processes and underling different daily life activities and school learning skills. Empowering EF becomes therefore crucial in children with CP both to strengthen specific functional EF weaknesses and to achieve far transfer effects on other compromised domains, such as motor planning, academic skills,and/or visuospatial processing. To pursue this, the EF training needs to be integrated into the complex and multidisciplinary care context promoting innovative intervention methodologies based on scientific evidence. Recent researches and clinical practice, carried out in our Institute, supports the effectiveness of innovative interventions on EF using new technologies in typical and atypical development, such as Self-adapting web based softwares, Game-based tools or Educational Robotics. Literature suggests these technologies allow to promote timely intervention within a user-friendly context, while respecting the key criteria of evidence-based neuropsychological rehabilitation, both reducing hospitalisation times and supporting interest and motivation for participation. The primary aim of this study is to evaluate the applicability of technological intervention integrated with psychomotor activities to promote EF and then secondary to measure the effect on the functional profile of children with CP, including motor planning, visuo-spatial processing and learning skills, evaluating both short-term (T2) and long-term changes (T3).

Eligibility criteria

Qualifiers

Children with confirmed diagnosis of CP

Ages from 5 to 13 years old

At least one cognitive index > 85 at WPPSI-IV or WISC-IV

Functional weakness in EF

Disqualifiers

Severe comorbidities and/or severe cognitive disability

Ages from 5 to 13 years old

No documented clinically relevant disorders

Trial design

Treatments tested in this trial

  • Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities
  • Tele-rehabilitation of EF and specific cognitive processes underlying academic skills
  • Game-based tools for the rehabilitation of EF and motor planning

Treatment groups

40 Participants
are divided into 4 treatment groups

Sponsors and collaborators

IRCCS Fondazione Stella Maris

Lead sponsor

University of Pisa

Collaborator

University of Florence

Collaborator

Anastasis Società Cooperativa Sociale

Collaborator