Health Trials

Personalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic Encephalopathy

ConditionsCirrhosisRefractory AscitesTIPS Insertion
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorMcGill University Health Centre/Research Institute of the McGill University Health Centre

About this trial

This study will evaluate whether a nutritional intervention is better than another to reduce the incidence of overt hepatic encephalopathy in patients undergoing TIPS insertion for refractory ascites.

Eligibility criteria

Qualifiers

Diagnosis of cirrhosis

TIPS planned for refractory ascites

Being at least moderately malnourished

Disqualifiers

TIPS insertion for other reason than refractory ascites

Budd Chiari Syndrome

Complete or cavernomatous portal vein thrombosis

Pre-TIPS recurrent or persistent overt hepatic encephalopathy

Trial design

Treatments tested in this trial

  • High Energy and High Protein Diet 1
  • High Energy and High Protein Diet 2

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

McGill University Health Centre/Research Institute of the McGill University Health Centre

Lead sponsor

Canadian Institutes of Health Research (CIHR)

Collaborator

Source ClinicalTrials.gov