Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorSenthil Sadhasivam
About this trial
The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants
Eligibility criteria
Qualifiers
None
Disqualifiers
Health conditions including uncontrolled diabetes (gestational or pre-existing) or hypertension (pre-eclampsia, eclampsia, or chronic)
Any history of opioid misuse before or during pregnancy-per self-report and clinical notes
Preoperative severe pain and opioid use/misuse, allergy to oxycodone
Allergy to oxycodone
Trial design
Treatments tested in this trial
- Preoperative Genotyping
Treatment groups
700 Participants
are divided into 2 treatment groupsSponsors and collaborators
Senthil Sadhasivam
Lead sponsor
University of Pittsburgh
Sponsor institution
National Center for Advancing Translational Sciences (NCATS)
Collaborator
Source ClinicalTrials.gov