Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-21
SponsorSenthil Sadhasivam
About this trial
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
Eligibility criteria
Qualifiers
Children ages 10 to 21
ASA physical status 1 to 3
Undergoing Posterior-Lateral Spinal Fusion
Receives in-patient opioids
Disqualifiers
Serious illness
Preoperative severe pain
Preoperative opioid use or misuse
Trial design
Treatments tested in this trial
- Preoperative Genotyping
Treatment groups
300 Participants
are divided into 1 treatment groupSponsors and collaborators
Senthil Sadhasivam
Lead sponsor
University of Pittsburgh
Sponsor institution
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov