Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorZhongda Hospital
About this trial
This observational study will explore the effects of PEEP and position on regional lung ventilation-perfusion mismatch by electrical impedance tomography (EIT) in moderate-to-severe ARDS patients with different lung recruitability.
Eligibility criteria
Qualifiers
age ≥18 years
Moderate-to-severe ARDS as per the 2023 ESICM definition
Undergoing invasive mechanical ventilation
Planned prone position based on the attending physicians' decisions
Disqualifiers
age ≥85 years
Pregnancy
Severe hemodynamic instability (> 30% increase in vasopressors in the last 6 hours or norepinephrine > 0.5 µg/kg/min)
Clinically suspected elevated intracranial pressure (>18 mm Hg)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov